Aggressive Non-Hodgkin’s Lymphomas in Immunocompromised

نویسندگان

  • Steven P. Kalter
  • Shirley A. Riggs
  • Fernando Cabanillas
  • James J. Butler
  • Fredrick B. Hagemeister
  • Peter W. Mansell
  • Guy R. Newell
  • Evan M. Hersh
چکیده

During the period from 1981 through 1984. 14 immunocompromised homosexual males with intermediate or high-grade non-Hodgkin’s lymphoma were seen at University of Texas M.D. Anderson Hospital and Tumor Institute. Six patients had diffuse large-cell lymphoma. seven had diffuse undifferentiated lymphoma. and one had unclassifiable lymphoma that suggested large-cell lymphoma. Eight patients had the acquired immunodeficiency syndrome (AIDS) and five had the AIDS-related complex. Kaposi’s sarcoma was initially present in four patients and developed later in two others. The patients with diffuse largecell lymphoma were characterized by more severely altered immune parameters. multicentric brain mass lesions. pretherapy opportunistic infections. lower perfor-

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تاریخ انتشار 2005